Skin Structure.

WHY MESOTHERAPY?

Well, mesotherapy is all about feeding your skin with all the nutrients it needs to look healthy and vibrant. However, unless these nutrients can be delivered to its site of action, into the inner layers of the skin, the efficiency of the feeding process is compromised. In similar way your baby will stay hungry if the food you give him goes elsewhere, but not in his mouth.

The phenomenal advances in the fields of biotechnology and molecular biology led to the development of sophisticated skin care products containing not only beneficial to skin vitamins, minerals and aminoacids but also peptides, proteins and polysaccharides. Proteins and polysaccharides are the building blocks of our skin, and the skin starts ageing when the shortage of the building materials takes place at the building site.

Evolution has provided the mammalian organism with an external covering, the principal function of which is to act as a barrier, specifically to the loss of tissue water. Just think: the concentration of water inside the human body is in the order of 50M, while that in the atmosphere is clearly very much less. Thus, there is a strong driving force for water to be lost from the body, and to prevent desiccation, an efficient barrier at the interface is therefore required. The skin’s outermost layer, the stratum corneum, provides this shield. In doing so, the skin presents a formidable resistance to the absorption of molecules which contact the external surface.

As you may see from the picture of the Skin Structure above, the epidermis is stratified, keratinising epithelium. The keratinocytes comprise the major cellular component (>90%) and are responsible for the evolution of barrier function. The stratum corneum is usefully thought of as a ‘brick wall’ with the corneocytes comprising the ‘bricks’, embedded in the ‘mortar’ created by intercellular lipids.

Thus, due to very tight ‘mortar’ junctions, the absorption of molecules from topically applied cosmetic creams, serums and lotions will be limited to very small size molecules such as vitamins, minerals, aminoacids and at most small peptides. Large molecules such as proteins (e.g. collagen) and polysaccharides (e.g. hyaluronic acid) are not able to penetrate through stratum corneum barrier. The only possible way of absorption for these molecules by passive diffusion into the skin is via hair follicles and sweat ducts that in total constitute only half percent of the skin surface area. This can not be considered efficient in terms of therapeutic macromolecules bioavailability. Therefore assisted penetration using subcutaneous and intradermal injections of therapeutic peptides, proteins and polysaccharides or transdermal mesotherapy method are the most effective ways of delivering crucial to ageing skin ‘building materials’ to the site of action.

Results of the observation studies into the efficacy of homeopathic remedies in the treatment of wrinkles and slackening of the face and neck tissues, are as follows:  

1. Skin nourishment with enhanced bioavailability of nutrients due to intradermal delivery using mesotherapy injection technique or transdermal delivery using special devices (No-needle Trasdermal Mesotherapy).
2. Antioxidative action on the skin
3. Stimulation of skin collagen and hyaluronan synthesis
4. Stimulation of skin microcirculation
5. Drainage and restoration of skin metabolic rate
6. Skin revitalisation and tonification

Homeopathic remedies for mesotherapy are mainly complex cocktails of homeopathic and natural to the body components such as vitamins, aminoacids, Krebs cycle catalysts, coenzymes, proteins such as collagen and elastin and glucosaminoglycans such as hyaluronic acid – all prepared homeopathically in the lowest homeopathic dilutions. When administered over a full course of in average eight treatments they provide visible and long lasting results.

Homeopathic medicines have no side effects or contraindications and can be used even during pregnancy. No patch tests are therefore required.

The remedies such as Bioteg, OTICatal, homeopathic elastin, hyaluronic acid, DMAE (OTI Srl.); MADE® (Guna Srl.); collagen (OTI Srl., Heel GmbH, Guna Srl.) can be used both as a treatment for reducing the signs of aging and as preventive treatment for maintaining youthful face. Lecitin, Dehydrocholic acid, Triac, Cellitin, Fucus, Procainum Composto (OTI Srl.) and many others are used for the treatment of cellulite and for body contouring. The remedies manufactured by OTI Srl. are suitable for transdermal mesotherapy.

Homeopathic remedies for facial mesotherapy not only add volume and smooth out imperfections (this is a shorter term effect compared to the fillers and Botox), but mainly produce accumulative and longer lasting regenerating effect on the dermis.

HOW MANY TREATMENTS DO I NEED?

Prices for face areas:

One area: £59.00
Two areas: £69.00
Three areas: £79.00

Prices for cellulite areas:

One area: £75.00
Two areas: £85.00
Three areas: £95.00

WHAT DO I NEED TO KNOW BEFORE THE TREATMENT?

Before you are treated, you skin must be clean, and any makeup or cosmetics removed using preferably astringent or facial cleansing lotion. Use cold water to ensure that your pores are not dilated. It is strongly recommended that no anti-inflammatory and/or anticoagulation drugs such as Aspirin or Warfarin are taken at least 3 to 4 days prior to your treatment as they may increase bruising and swelling at the injection site.

The effects of homeopathic injectable medicines may include temporary mild inflammatory reaction such as redness in the injected area and temporary swelling and/or nodules or mild bruising at the injection site.

You will be asked to complete Medical History and Patient Consent forms before the first treatment and also will be given a Book of Patient Treatment Records.

Your practitioner will insert a fine short needle in the desired location. Swelling and redness will usually subside within hours and you can get back to your daily routine with little down time. Topical anaesthetic cream can be used to minimise discomfort of the procedure.

After the treatment try to keep your face relaxed and refrain from exposure to extreme heat (sauna, bath, sunbathing) for one week after the treatment. This can cause the components of homeopathic injectable medicines to break down more rapidly. It is not advisable to touch or massage the injected area. You can begin to re-apply your makeup the day after your treatment.

BODY CONTOURING AND TREATMENT OF CELLULITE

CONTRAINDICATIONS FOR NEEDLE USAGE:

Homeopathic injectable medicines are only available through medical professionals or qualified in mesotherapy registered practitioners.

The ideal candidates for Aesthetic Bioregulatory Homeomesotherapy are men and women looking to improve or restore their skin texture and firmness, maintain youthful look, smooth out shallow wrinkles and imperfections on their face and improve their body contour.

REFERENCES:

1. OmeoNet Journal, pilot issue 2008
2. Martines Image course lectures, 2009
3. Biological Mesotherapy in Aesthetic Medicine by Dr. E. Sazhina. Holistic Cure, 2008
4. Stedman’s Medical Dictionary, 5th edition. Lippincott Williams & Wilkins, 2005
5. Clinical Medicine, by Kumar & Clark, 6th edition. Elsevier Saunders, 2005
6. Drug Delivery and Targeting for Pharmacists and Pharmaceutical Scientists. Taylor & Francis, 2001